Concepedia

Enantioselective synthesis of (−)-paeonilide

Klaus Harrar, Oliver Reiser

Chemical Communications · 2012 · 51 citations · 19 references

DOI

Concepts

Abstract

The first enantioselective synthesis of (-)-paeonilide is reported. Starting from inexpensive furan-3-carboxylic acid the targeted monoterpene was obtained in 12 steps via an asymmetric cyclopropanation-lactonization cascade and a stereoselective side chain insertion at an acetal-like position.

References

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