NF-κB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

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Medicine, Oncology, Pharmacology +17

NF-κB functions as a tumour promoter in inflammation-associated cancer

Eli Pikarsky, Rinnat M. Porat, Ilan Stein et al. · Nature · 2004 · 2.4K citations

Life Sciences, Cancer Biology, Oncology +16

IKKβ Couples Hepatocyte Death to Cytokine-Driven Compensatory Proliferation that Promotes Chemical Hepatocarcinogenesis

Shin Maeda, Hideaki Kamata, Jun‐Li Luo et al. · Cell · 2005 · 1.2K citations · Full text

Life Sciences, Cell Biology, Oncology +16

The Continuing Increase in the Incidence of Hepatocellular Carcinoma in the United States: An Update

Hashem B. El‐Serag, Jessica A. Davila, Nancy J. Petersen et al. · Annals of Internal Medicine · 2003 · 944 citations · Full text

Medicine, Biostatistics, Oncology +17

Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation

Mireille Delhase, Makio Hayakawa, Yi Chen et al. · Science · 1999 · 869 citations

Life Sciences, Cell Biology, Molecular Biology +16