Identification and Pharmacological Profile of a New Class of Selective Nicotinic Acetylcholine Receptor Potentiators

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.9K citations

Life Sciences, Biochemistry, Pharmacology +14

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor:<i>In Vitro</i>and<i>In Vivo</i>Characterization

Raymond S Hurst, Mihály Hajós, M. Raggenbass et al. · Journal of Neuroscience · 2005 · 444 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Chimaeric nicotinic–serotonergic receptor combines distinct ligand binding and channel specificities

Jean-Luc Eiselé, Sonia Bertrand, Jean‐Luc Galzi et al. · Nature · 1993 · 408 citations

Life Sciences, Neuroscience, Pharmacology +12

17β-Estradiol Potentiates Kainate-Induced Currents via Activation of the cAMP Cascade

Qin Gu, Robert L. Moss · Journal of Neuroscience · 1996 · 346 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17