Zygotic Lethal Mutations With Maternal Effect Phenotypes in <i>Drosophila melanogaster</i>. II. Loci on the Second and Third Chromosomes Identified by <i>P</i>-Element-Induced Mutations

Abstract

Screens for zygotic lethal mutations that are associated with specific maternal effect lethal phenotypes have only been conducted for the X chromosome. To identify loci on the autosomes, which represent four-fifths of the Drosophila genome, we have used the autosomal "FLP-DFS" technique to screen a collection of 496 P element-induced mutations established by the Berkeley Drosophila Genome Project. We have identified 64 new loci whose gene products are required for proper egg formation or normal embryonic development.