Concepedia

Zygotic Lethality

Zygotic Lethality is a type of embryonic lethal mutation in which the developmental failure and subsequent death of the organism result specifically from the expression of mutant alleles in the zygote's own genome, rather than from maternal effect gene products.

101

Publications

9.2K

Citations

363

Authors

162

Institutions

Publications per year

2017–2026

5

Parents

Publications

101

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

Napoleone Ferrara, Karen Carver-Moore, Helen Chen et al. · Nature · 1996 · 3.7K citations · Full text

, , +11

<i>Drosophila</i> aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

Melissa M. Rolls, Roger Albertson, Hsin-Pei Shih et al. · The Journal of Cell Biology · 2003 · 287 citations · Full text

, , +17

Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster. I. Loci on the X chromosome.

Norbert Perrimon, Lee Engstrom, Anthony P. Mahowald · Genetics · 1989 · 202 citations · Full text

, , +17

A Novel Sperm-Delivered Toxin Causes Late-Stage Embryo Lethality and Transmission Ratio Distortion in &lt;em&gt;C. elegans&lt;/em&gt;

Hannah S. Seidel, Michael Ailion, Jialing Li et al. · Figshare · 2016 · 196 citations · Full text

, , +13

Ectopic expression of the H19 gene in mice causes prenatal lethality.

Mary E. Brunkow, S M Tilghman · Genes & Development · 1991 · 177 citations · Full text

, , +14

1–5 of 101

Authors

363

  1. NP
    Norbert Perrimon

    Harvard University, United States

    8 publications · 952 citations

    8

    h-index

  2. AP
    Anthony P. Mahowald

    Case Western Reserve University, United States

    6 publications · 694 citations

    6

    h-index

  3. LE
    Lee Engstrom

    Case Western Reserve University, United States

    4 publications · 572 citations

    4

    h-index

  4. LG
    Leonard G Robbins

    Michigan State University, United States

    3 publications · 78 citations

    3

    h-index

  5. EJ
    Edward J. Klekowski

    University of Massachusetts Amherst, United States

    3 publications · 96 citations

    3

    h-index

1–5 of 363

Institutions

162

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    19 publications

    3.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    20 publications

    875 citations

  3. Case Western Reserve University

    Cleveland, United States

    5 h-index

    12 publications

    1.2K citations

  4. Michigan State University

    East Lansing, United States

    4 h-index

    4 publications

    104 citations

  5. Johns Hopkins University

    Baltimore, United States

    4 h-index

    8 publications

    427 citations

  6. University of Alberta

    Edmonton, Canada

    3 h-index

    9 publications

    421 citations

  7. National Institutes of Health

    Bethesda, United States

    3 h-index

    10 publications

    206 citations

  8. Harvard University

    Cambridge, United States

    3 h-index

    6 publications

    447 citations

1–8 of 162

Venues

  1. Genetics

    39 publications · 2.2K citations

    27

    h-index

  2. Developmental Biology

    4 publications · 365 citations

    4

    h-index

  3. Developmental Genetics

    4 publications · 77 citations

    4

    h-index

  4. Development

    4 publications · 337 citations

    4

    h-index

  5. Molecular and General Genetics MGG

    4 publications · 133 citations

    4

    h-index

1–5