Antagonism of SET Using OP449 Enhances the Efficacy of Tyrosine Kinase Inhibitors and Overcomes Drug Resistance in Myeloid Leukemia - Concepedia

Concepedia

Publication | Open Access

Antagonism of SET Using OP449 Enhances the Efficacy of Tyrosine Kinase Inhibitors and Overcomes Drug Resistance in Myeloid Leukemia

DOI Full Paper Access

123

Citations

37

References

2014

Year

Anupriya Agarwal, Ryan J. MacKenzie, Raffaella Pippa, Christopher A. Eide, Jessica Oddo, Jeffrey Tyner, Rosalie C. Sears, Michael P. Vitek, María D. Odero, Dale J. Christensen,

Clinical Cancer Research

Abstract

We demonstrate a novel therapeutic paradigm of SET antagonism using OP449 in combination with tyrosine kinase inhibitors for the treatment of CML and AML.

References

	Year	Citations

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