RETRACTION: 5-aza-Cytidine Is a Potent Inhibitor of DNA Methyltransferase 3a and Induces Apoptosis in HCT-116 Colon Cancer Cells via Gadd45- and p53-Dependent Mechanisms

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Randomized Controlled Trial of Azacitidine in Patients With the Myelodysplastic Syndrome: A Study of the Cancer and Leukemia Group B

Lewis R. Silverman, Erin P. Demakos, Bercedis L. Peterson et al. · Journal of Clinical Oncology · 2002 · 1.8K citations

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Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21 ^WAF1

Linda S.-H. Chuang, Hang-In Ian, Tong‐Wey Koh et al. · Science · 1997 · 894 citations

Life Sciences, Genetics, Molecular Biology +10

The <i>DNMT3B</i> DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome

R. Scott Hansen, Cisca Wijmenga, Ping Luo et al. · Proceedings of the National Academy of Sciences · 1999 · 730 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation.

R Jüttermann, E Li, Rudolf Jaenisch · Proceedings of the National Academy of Sciences · 1994 · 684 citations · Full text

Medicine, Molecular Biology, Pharmacology +11