Angewandte Chemie International Edition · 2009 · 179 citations · 55 references
Natural SciencesChemistryCatalysisOrganic ChemistrySynthetic Medicinal ChemistryHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisBenzofuran ChemistryCopper-catalyzed CouplingHydroxylation ReactionsMild Reaction ConditionsTransition Metal-catalyzed Synthesis
A smooth operator: The copper-catalyzed synthesis of phenols from aryl halides was carried out under relatively mild reaction conditions. Alkyl aryl ethers and benzofurans could also be prepared smoothly by one-pot domino protocols based on hydroxylation of aryl iodides (see scheme).
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