Synthesis of Phenol, Aromatic Ether, and Benzofuran Derivatives by Copper‐Catalyzed Hydroxylation of Aryl Halides

Dongbing Zhao, Ningjie Wu, Shuai Zhang, Peihua Xi, Xiaoyu Su, Jingbo Lan, Jingsong You

Angewandte Chemie International Edition · 2009 · 179 citations · 55 references

Concepts

Abstract

A smooth operator: The copper-catalyzed synthesis of phenols from aryl halides was carried out under relatively mild reaction conditions. Alkyl aryl ethers and benzofurans could also be prepared smoothly by one-pot domino protocols based on hydroxylation of aryl iodides (see scheme).

References

55