The Binding of Cations by Chondroitin Sulfate

Abstract

Chondroitin sulfate, isolated from beef nasal cartilage, was prepared as the crystalline calcium salt by methods previously described (10). This calcium salt was con- verted to the sodium or potassium salt by the use of the sodium or potassium form of Dowex-50. Chondromucoprotein as the potassium salt and desulfated chondroitin sulfate as the methyl ester were prepared by methods described elsewhere (11, 12). For convenience these substances will be referred to as Na2ChS, KChS, or