Integrin α1β1 and Transforming Growth Factor-β1 Play Distinct Roles in Alport Glomerular Pathogenesis and Serve as Dual Targets for Metabolic Therapy

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

Wayne A. Border, Seiya Okuda, Lucia R. Languino et al. · Nature · 1990 · 1K citations

Glomerular Disease, Renal Pathology, Immunology +17

Identification of Mutations in the COL4A5 Collagen Gene in Alport Syndrome

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Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments.

Patricia Rousselle, Gregory P. Lunstrum, Douglas R. Keene et al. · The Journal of Cell Biology · 1991 · 740 citations · Full text

Protein Secretion, Cell Adhesion, Immunology +21

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

Jordan A. Kreidberg, Michael J. Donovan, Stuart L. Goldstein et al. · Development · 1996 · 709 citations

The Laminin α Chains: Expression, Developmental Transitions, and Chromosomal Locations of α1-5, Identification of Heterotrimeric Laminins 8–11, and Cloning of a Novel α3 Isoform

Jeffrey H. Miner, Bruce L. Patton, Stephen I. Lentz et al. · The Journal of Cell Biology · 1997 · 658 citations · Full text