THE EFFECT OF ADENO-ASSOCIATED VIRUS MEDIATED BRAIN DERIVED NEUROTROPHIC FACTOR IN AN ANIMAL MODEL OF NEUROGENIC IMPOTENCE

Abstract

Intracavernous injection of adeno-associated virus-brain derived neurotrophic factor may prevent the degeneration of neuronal nitric oxide synthase containing neurons in the major pelvic ganglia and facilitate the regeneration of neuronal nitric oxide synthase containing nerve fibers in penile tissue, thus, enhancing the recovery of erectile function after bilateral cavernous nerve injury.