Effects of probiotic therapy in critically ill patients: a randomized, double-blind, placebo-controlled trial

APACHE II

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1985 · 13.7K citations

Medicine, Internal Medicine, Clinical Classification Systems +16

APACHE II-A Severity of Disease Classification System

William A. Knaus, Elizabeth A. Draper, Douglas P. Wagner et al. · Critical Care Medicine · 1986 · 13.4K citations

Health Professions, Biostatistics, Clinical Classification Systems +12

The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

Jean‐Louis Vincent, Rui P. Moreno, Jukka Takala et al. · Intensive Care Medicine · 1996 · 11.6K citations

Veterinary Medicine, Internal Medicine, Critical Care Medicine +12

Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units

Jean‐Louis Vincent, Arnaldo de Mendonça, F. Cantraine et al. · Critical Care Medicine · 1998 · 3.5K citations

Medicine, Surgery, Critical Care Medicine +12

Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: A double-blind, placebo-controlled trial

Paolo Gionchetti, Fernando Rizzello, Alessandro Venturi et al. · Gastroenterology · 2000 · 1.5K citations · Full text

Pharmacy, Oral Medicine, Pharmacotherapy +6