Green protocol for annulation of the s-triazine ring on thiazoles using a three-component coupling strategy

Abstract

Novel three-component one-pot reactions of thiazole Schiff bases, ammonium acetate, and aromatic aldehydes under solvent-free microwave irradiation conditions expeditiously and diastereoselectively annulate the s-triazine ring on thiazoles to yield thiazolo-s-triazines.