Ocular manifestations in Fabry disease: a survey of 32 hemizygous male patients

Abstract

Corneal involvement, especially haze, was the most constant manifestation. The frequency of cornea verticillata was less than expected from the literature. We suggest that the haze is the natural evolution of cornea verticillata. Vascular abnormalities of the conjunctiva and the retina were frequent. Enlargement of the blind spot could possibly be related to subclinical optic neuropathy.