Angewandte Chemie International Edition · 2012 · 91 citations · 21 references
Natural SciencesBioengineeringBiotechnologyBiocompatibilityBiomaterialsDrug DeliveryBiodegradable PolymersDrug EncapsulationSelf-healing MaterialsEncapsulationMicrocapsule-based Self-healingMicroencapsulationMicroencapsulation ProcessesPoly(lactic-co-glycolic Acid)Poly(lactic-co-glycolic Acid) SystemsPolymeric MicrocapsulesProtein Encapsulation
Capture and seal off all exits! Biomacromolecules are routinely microcapsulated in poly(lactic-co-glycolic acid) (PLGA) in multiple complex steps that are deleterious to the biomacromolecule. In contrast, PLGA encapsulation based on self-healing (see picture) shows high efficiency without protein damage and enables the stabilization and slow release of proteins. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Biodegradable Long-Circulating Polymeric Nanospheres
Ruxandra Gref, Yoshiharu Minamitake, Maria Teresa Peracchia et al. · Science · 1994 · 2.9K citations
Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents
Gregg W. Stone, Jeffrey W. Moses, Stephen G. Ellis et al. · New England Journal of Medicine · 2007 · 1.6K citations · Full text