Overexpression of HMGA2 Promotes Metastasis and Impacts Survival of Colorectal Cancers

Abstract

Overexpression of HMGA2 is associated with metastasis and unequivocally occurred in parallel with reduced survival rates of patients with CRC. Therefore, HMGA2 may potentially serve as a biomarker for predicting aggressive CRC with poor survivability and as an indicator for better response of radiotherapy.