Concepedia

Glucocorticoids Promote Hepatic Cholestasis in Mice by Inhibiting the Transcriptional Activity of the Farnesoid X Receptor

Yan Lu, Zhijian Zhang, Xuelian Xiong, Xiaolin Wang, Jin Li, Guojun Shi, Jian Yang, Xianfeng Zhang, Huijie Zhang, Jie Hong,

Gastroenterology · 2012 · 61 citations · 46 references

DOIFull text

Open access

Concepts

References

46

Identification of a Nuclear Receptor for Bile Acids

Makoto Makishima, Arthur Y. Okamoto, Joyce J. Repa et al. · Science · 1999 · 2.7K citations

, , +17

A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis

Bryan Goodwin, Stacey A. Jones, Roger R. Price et al. · Molecular Cell · 2000 · 1.9K citations · Full text

, , +16

Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis

Christopher J. Sinal, Masahiro Tohkin, Masaaki Miyata et al. · Cell · 2000 · 1.8K citations · Full text

, , +12

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

Yanqiao Zhang, Florence Ying Lee, Gabriel Barrera et al. · Proceedings of the National Academy of Sciences · 2006 · 937 citations · Full text

, , +17

Farnesoid X receptor is essential for normal glucose homeostasis

Ke Ma · Journal of Clinical Investigation · 2006 · 863 citations · Full text

, , +17