Oxidative stress mediated Ca2+ release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

Heather P. Harding, Yuhong Zhang, David Ron · Nature · 1999 · 3.3K citations

Life Sciences, Biochemistry, Molecular Biology +10

Gadd153 Sensitizes Cells to Endoplasmic Reticulum Stress by Down-Regulating Bcl2 and Perturbing the Cellular Redox State

Karen D. McCullough, Jennifer L. Martindale, Lars‐Oliver Klotz et al. · Molecular and Cellular Biology · 2001 · 1.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

Hamsa Puthalakath, Lorraine A. O’Reilly, Priscilla Gunn et al. · Cell · 2007 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Feedback Inhibition of the Unfolded Protein Response by <i>GADD34</i>-Mediated Dephosphorylation of eIF2α

Isabel Novoa, Huiqing Zeng, Heather P. Harding et al. · The Journal of Cell Biology · 2001 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Vitamin A Antagonizes Decreased Cell Growth and Elevated Collagen-Degrading Matrix Metalloproteinases and Stimulates Collagen Accumulation in Naturally Aged Human Skin1

James Varani, Roscoe L. Warner, Mehrnaz Gharaee‐Kermani et al. · Journal of Investigative Dermatology · 2000 · 636 citations · Full text

Education, Dermatology, Nutritional Sciences +15