Concepedia

Statin cardiomyopathy? A potential role for Co‐Enzyme Q<sub>10</sub> therapy for statin‐induced changes in diastolic LV performance: Description of a clinical protocol

Marc A. Silver, Peter H. Langsjoen, Szabolcs Szabo, Harish Patil, Allan Zelinger

BioFactors · 2003 · 15 citations · 12 references

DOI

Abstract

Statistical analysis will be performed using the paired t test to compare coenzyme levels and echocardiographic indices at baseline and after treatment and after supplementation.

References

12

Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy. Relation to symptoms and prognosis.

Charanjit S. Rihal, Rick A. Nishimura, L K Hatle et al. · Circulation · 1994 · 443 citations · Full text

Lovastatin decreases coenzyme Q levels in humans.

Karl Folkers, Peter H. Langsjoen, Richard A. Willis et al. · Proceedings of the National Academy of Sciences · 1990 · 426 citations · Full text

Evidence of Plasma CoQ10‐Lowering Effect by HMG‐CoA Reductase Inhibitors: A Double‐Blind, Placebo‐Controlled Study

Giovanni Ghirlanda, A. Oradei, Andrea Manto et al. · The Journal of Clinical Pharmacology · 1993 · 325 citations

Lipid‐lowering drugs and mitochondrial function: effects of HMG‐CoA reductase inhibitors on serum ubiquinone and blood lactate/pyruvate ratio

Gonzague de Pinieux, Patrick Chariot, Mohamed Tarek Ammisaid et al. · British Journal of Clinical Pharmacology · 1996 · 263 citations · Full text

Biochemical rationale and myocardial tissue data on the effective therapy of cardiomyopathy with coenzyme Q10.

Karl Folkers, Surasi Vadhanavikit, Svend Aage Mortensen · Proceedings of the National Academy of Sciences · 1985 · 244 citations · Full text

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