Concepedia

Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, As First-Line Therapy in Patients With Metastatic Breast Cancer Previously Treated With Anthracycline Chemotherapy

Henri Roché, Louise Yelle, Francesco Cognetti, L. Mauriac, Craig A. Bunnell, Joseph A. Sparano, Pierre Kerbrat, Jean‐Pierre Delord, Linda T. Vahdat, Ronald Peck,

Journal of Clinical Oncology · 2007 · 225 citations · 20 references

DOI

Abstract

Ixabepilone is efficacious and has a predictable and manageable safety profile in women with MBC previously treated with an adjuvant anthracycline.

References

20

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Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action

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Randomized Phase III Study of Docetaxel Compared With Paclitaxel in Metastatic Breast Cancer

Stephen E. Jones, John K. Erban, Beth Overmoyer et al. · Journal of Clinical Oncology · 2005 · 546 citations · Full text

Prospective Randomized Trial of Docetaxel Versus Mitomycin Plus Vinblastine in Patients With Metastatic Breast Cancer Progressing Despite Previous Anthracycline-Containing Chemotherapy

Jean‐Marc Nabholtz, H.-J. Senn, W.R. Bezwoda et al. · Journal of Clinical Oncology · 1999 · 506 citations