Publication | Open Access

Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): A γ-secretase inhibitor with Aβ lowering activity in a transgenic mouse model of Alzheimer’s disease

Neurochemical BiomarkersTransgenic Mouse ModelAlzheimer ’Pharmaceutical ChemistryMolecular PharmacologyMedicinal ChemistryAlzheimer's DiseaseNeurochemistryBiochemistryMechanism Of ActionPharmacological AgentNeuropharmacologyPharmacologyNeurodegenerative DiseasesNatural SciencesNeuroscienceγ-Secretase InhibitorMedicineDrug Discovery