Publication | Closed Access
Genome Data Shake Tree of Life
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1998
Year
Comparative GenomicsGeneticsGenomicsArchaeaMicrobial EvolutionPhylogeneticsMolecular EcologyCell NucleiComputational GenomicsSequence AnalysisPhylogenomicsGene EvolutionBioinformaticsNew WealthFunctional GenomicsBiologyMicrobial SystematicsNatural SciencesEvolutionary BiologyComputational BiologyMedicineSequence AssemblyEvolutionists9 Tree
The new wealth of microbial genome sequences is threatening to overturn evolutionists9 tree of life. In the current tree, a universal common ancestor gave rise to the two microbial branches, the archaea and bacteria (which lack cell nuclei), and the archaea then gave rise to the eukarya (all organisms that have cell nuclei). But the new sequences show that genes don9t evolve at the same rate or in the same way, so the evolutionary history inferred from one gene may be different from what another gene appears to show. Even more perplexing, some genomes have been found to contain a mix of DNAs from both the archaea and the bacteria. Many evolutionary biologists are coming to believe that these mosaics arose because genes hopped from branch to branch as early organisms either stole genes from their food or swapped DNA with their neighbors. If this gene swapping was extensive enough, the tree9s base may turn out to be indecipherable: a network of branches that merge and split and merge again before sprouting the modern kingdoms.