Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia.

Malcolm A. Smith, D Arthur, Bruce M. Camitta et al. · Journal of Clinical Oncology · 1996 · 916 citations

Medicine, Hematology, Oncology +13

Methyltransferase Recruitment and DNA Hypermethylation of Target Promoters by an Oncogenic Transcription Factor

Luciano Di Croce, Veronica A. Raker, Massimo Corsaro et al. · Science · 2002 · 780 citations

Medicine, Genetics, Molecular Biology +17

Methylation of the p15INK4b Gene in Myelodysplastic Syndromes Is Frequent and Acquired During Disease Progression

Bruno Quesnel, Gaëlle Guillerm, Rodolphe Vereecque et al. · Blood · 1998 · 346 citations

Life Sciences, Genetics, Molecular Genetics +12

Hypermethylation of the DAP-Kinase CpG Island Is a Common Alteration in B-Cell Malignancies

Rachel A. Katzenellenbogen, Stephen B. Baylin, James G. Herman · Blood · 1999 · 312 citations

Medicine, Molecular Biology, Molecular Genetics +16