Concepedia

Novel Lipid Droplet–Associated Serine Hydrolase Regulates Macrophage Cholesterol Mobilization

Young‐Hwa Goo, Se‐Hee Son, Paul B. Kreienberg, Antoni Paul

Arteriosclerosis Thrombosis and Vascular Biology · 2013 · 54 citations · 25 references

DOIFull text

Open access

Abstract

The data identify a candidate target to promote reverse cholesterol transport from atherosclerotic lesions.

References

25

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

Bo Feng, Pin Mei Yao, Yankun Li et al. · Nature Cell Biology · 2003 · 865 citations

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Autophagy Regulates Cholesterol Efflux from Macrophage Foam Cells via Lysosomal Acid Lipase

Mireille Ouimet, Vivian Franklin, Esther Mak et al. · Cell Metabolism · 2011 · 735 citations · Full text

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The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters.

Michael S. Brown, Y K Ho, Joseph L. Goldstein · Journal of Biological Chemistry · 1980 · 729 citations · Full text

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Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins.

Michael S. Brown, J L Goldstein, Monty Krieger et al. · The Journal of Cell Biology · 1979 · 548 citations · Full text

, , +14

Transdifferentiation of mouse aortic smooth muscle cells to a macrophage-like state after cholesterol loading

James X. Rong, Mark S. Shapiro, Eugene Trogan et al. · Proceedings of the National Academy of Sciences · 2003 · 536 citations · Full text

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