Publication | Closed Access
A COMPARISON OF ANALYSIS METHODS FOR LATE‐STAGE VARIETY EVALUATION TRIALS
96
Citations
19
References
2010
Year
Sample TreatmentGenetic EpidemiologyGenomic SelectionGeneralized Heritability MeasureGenotype-phenotype AssociationBreedingClinical TrialsRandomized Controlled TrialBiostatisticsPublic HealthStatisticsGenetic PredispositionReliabilityMethod ValidationQuantitative GeneticsOutcomes ResearchStatistical GeneticsGenetic VariationEvaluationPopulation GeneticsVariety PerformanceVariety PredictionsMedicine
Summary The statistical analysis of late‐stage variety evaluation trials using a mixed model is described, with one‐ or two‐stage approaches to the analysis. Two sets of trials, from Australia and the UK, were used to provide realistic scenarios for a simulation study to evaluate the different methods of analysis. This study showed that a one‐stage approach gave the most accurate predictions of variety performance overall or within each environment, across a range of models, as measured by mean squared error of prediction or realized genetic gain. A weighted two‐stage approach performed adequately for variety predictions both overall and within environments, but a two‐stage unweighted approach performed poorly in both cases. A generalized heritability measure was developed to compare methods.
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