Loss of Fgfr2 leads to partial XY sex reversal

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

Andrew Sinclair, Philippe Berta, Mark S. Palmer et al. · Nature · 1990 · 3.2K citations

Chromatin, Sex Determination, Dna-binding Motif +12

Consensus Statement on Management of Intersex Disorders

Peter A. Lee, Christopher P. Houk, S. Faisal Ahmed et al. · PEDIATRICS · 2006 · 2.3K citations

Family Medicine, Reproductive Health, Gynecology +16

Receptor Specificity of the Fibroblast Growth Factor Family

David M. Ornitz, Jennifer S. Colvin, Donald G. McEwen et al. · Journal of Biological Chemistry · 1996 · 1.9K citations · Full text

Fibrosis, Signal Transduction, Developmental Biology +15

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

Thomas Wagner, Jutta Wirth, Jobst Meyer et al. · Cell · 1994 · 1.6K citations

Developmental Biology, Mendelian Disorder, Genetic Disorder +7

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Jamie W. Foster, M. Dominguez-Steglich, Silvana Guioli et al. · Nature · 1994 · 1.6K citations

Developmental Anomaly, Developmental Biology, Mendelian Disorder +10