Lab on a Chip · 2012 · 206 citations · 19 references
EngineeringBioengineeringFluid DynamicsFluid MechanicsRheologyBiofluid MechanicsMicrofluidic DevicesMicrofluidic SystemsMicrofluidic TransportMicrofluidicsParticle-laden FlowsBistabilityMicrochannel FlowMicrofluidic FlowMicrofluidic Flow ExperimentsParticle Manipulation In MicrofluidicsParticle MigrationRheological PropertiesSingle-particle Manipulation
We perform 3D numerical simulations, heuristic modeling and microfluidic experiments to demonstrate, for the first time, the presence of a bistability scenario for transversal migration of particles suspended in a viscoelastic liquid flowing in a pipe. Our results show that particle migration, either at the centerline or at the wall, can be controlled by the rheological properties of the suspending liquid and by the relative dimensions of the particle and tube. Proper selection of these parameters can promote strict aligning of particles on a line, i.e., 3-D focusing. Simple design rules are given to rationally control particle focusing under flow in micropipes.
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A. Brooks, Thomas J.R. Hughes · Computer Methods in Applied Mechanics and Engineering · 1982 · 5.3K citations
Radial Particle Displacements in Poiseuille Flow of Suspensions
G Segré, A. Silberberg · Nature · 1961 · 1.2K citations
Engineering, Physics, Fluid Dynamics +10