LHON/MELAS overlap mutation in ND1 subunit of mitochondrial complex I affects ubiquinone binding as revealed by modeling in Escherichia coli NDH-1

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

Julie Thompson, Desmond G. Higgins, Toby J. Gibson · Nucleic Acids Research · 1994 · 64.9K citations · Full text

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One-step inactivation of chromosomal genes in <i>Escherichia coli</i> K-12 using PCR products

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Predicting transmembrane protein topology with a hidden markov model: application to complete genomes11Edited by F. Cohen

Anders Krogh, B. Larsson, Gunnar von Heijne et al. · Journal of Molecular Biology · 2001 · 13K citations

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Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection

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Life Sciences, Genetics, Microbiology +9

A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies

Yu‐ichi Goto, Ikuya Nonaka, Satoshi Horai · Nature · 1990 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +11