Concepedia

Toxicokinetics and Metabolism of N-[14C] N-Methyl-2-Pyrrolidone in Male Sprague-Dawley Rats: in Vivo and in Vitro Percutaneous Absorption

Jean-Paul Payan, Isabelle Boudry, Dominique Beydon, Jean-Paul Fabry, Marie-Christine Grandclaude, E Ferrari, Jean–Claude André

Drug Metabolism and Disposition · 2003 · 34 citations · 13 references

DOI

Concepts

References

13

Effect of penetration enhancers on the permeation of mannitol, hydrocortisone and progesterone through human skin

Brian Barry, Susan L. Bennett · Journal of Pharmacy and Pharmacology · 1987 · 187 citations

, , +16

Permeability of Commercial Solvents Through Living Human Skin

Christian Ursin, Charlès M. Hansen, John W. Van Dyk et al. · American Industrial Hygiene Association Journal · 1995 · 115 citations

, , +16

Acute toxicity of various solvents in the mouse and rat. LD50 of ethanol, diethylacetamide, dimethylformamide, dimethylsulfoxide, glycerine, N-methylpyrrolidone, polyethylene glycol 400, 1,2-propanediol and Tween 20.

W Bartsch, G Sponer, Katharina Dietmann et al. · PubMed · 1976 · 90 citations

, , +13

Major metabolic pathway for N-methyl-2-pyrrolidone in humans.

Bengt Åkesson, Bo Jönsson · PubMed · 1997 · 80 citations

, , +9

Experimental exposure of male volunteers to N-methyl-2-pyrrolidone (NMP): acute effects and pharmacokinetics of NMP in plasma and urine.

Benny Åkesson, Kajsa Paulsson · Occupational and Environmental Medicine · 1997 · 69 citations · Full text

, , +15