Macromolecule Loading into Spherical, Elliptical, Star‐Like and Cubic Calcium Carbonate Carriers

Bogdan V. Parakhonskiy, Alexey M. Yashchenok, Senem Donatan, Dmitry Volodkin, Francesco Tessarolo, R. Antolini, Helmuth Möhwald, André G. Skirtach

ChemPhysChem · 2014 · 95 citations · 37 references

Concepts

Abstract

We fabricated calcium carbonate particles with spherical, elliptical, star-like and cubical morphologies by varying relative salt concentrations and adding ethylene glycol as a solvent to slow down the rate of particle formation. The loading capacity of particles of different isotropic (spherical and cubical) and anisotropic (elliptical and star-like) geometries is investigated, and the surface area of such carriers is analysed. Potential applications of such drug delivery carriers are highlighted.

References

37