Angiotensin II-Induced Cyclooxygenase 2 Expression in Rat Aorta Vascular Smooth Muscle Cells Does Not Require Heterotrimeric G Protein Activation

Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds

Louis M. Luttrell, Francine L. Roudabush, Eric W. Choy et al. · Proceedings of the National Academy of Sciences · 2001 · 818 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).

Tsutomu Higashijima, Sonoko Uzu, Terumi Nakajima et al. · Journal of Biological Chemistry · 1988 · 679 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2

Huijun Wei, Seungkirl Ahn, Sudha K. Shenoy et al. · Proceedings of the National Academy of Sciences · 2003 · 669 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Molecular Determinants Underlying the Formation of Stable Intracellular G Protein-coupled Receptor-β-Arrestin Complexes after Receptor Endocytosis*

Robert H. Oakley, Stéphane A. Laporte, Jason A. Holt et al. · Journal of Biological Chemistry · 2001 · 449 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors

Kristen L. Pierce, Stuart Maudsley, Yehia Daaka et al. · Proceedings of the National Academy of Sciences · 2000 · 223 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17