Organic & Biomolecular Chemistry · 2011 · 29 citations · 23 references
PharmacyMedicinal ChemistryMicrobiologyDrug DiscoveryOrganic ChemistryStructure-activity RelationshipsNatural Product Drug DiscoveryAntibiotic Effects On GrowthBioactive HeterocyclesCytotoxicity Assays
Phenazinolins A-E (1-5), which possess a carbon skeleton unique to diphenazines (the azabicyclo[3.3.1]nonadienol moiety in 1-3 and the oxabicyclo[3.3.1]nonadienol moiety in 4 and 5), were isolated from tin mine tailings-derived Streptomyces diastaticus YIM DT26, with 1-3 exhibited appreciable cytotoxicity and antibiotic effects.
23