Arginase pathway in human endothelial cells in pathophysiological conditions

Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life.

M Yoshizumi, Mark A. Perrella, J. C. Burnett et al. · Circulation Research · 1993 · 776 citations · Full text

Life Sciences, Cardiology, Molecular Biology +7

Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels

Dan E. Berkowitz, Ronald D. White, Dechun Li et al. · Circulation · 2003 · 483 citations

Education, Cardiology, Pharmacology +17

Structure of a unique binuclear manganese cluster in arginase

Z.F. Kanyo, Laura R. Scolnick, David E. Ash et al. · Nature · 1996 · 441 citations

Natural Sciences, Chemistry, Molecular Biology +10

Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

Hui Li, Cynthia J. Meininger, James Hawker et al. · American Journal of Physiology-Endocrinology and Metabolism · 2001 · 391 citations

Life Sciences, Biochemistry, Molecular Biology +13

Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity.

Pnina Rosenkranz-Weiss, William C. Sessa, Sheldon Milstien et al. · Journal of Clinical Investigation · 1994 · 364 citations · Full text

Life Sciences, Biochemistry, Immunology +15