Concepedia

Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum

Roland A. Cooper, Michael T. Ferdig, Xin Su, Lyann M. B. Ursos, Jianbing Mu, Takashi Nomura, Hisashi Fujioka, David A. Fidock, Paul D. Roepe, Thomas E. Wellems

Molecular Pharmacology · 2002 · 240 citations · 39 references

DOI

Concepts

References

39

Synchronization of Plasmodium falciparum Erythrocytic Stages in Culture

C. Lambros, Jerome P. Vanderberg · Journal of Parasitology · 1979 · 3.8K citations · Full text

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Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

R. E. Desjardins, Craig J. Canfield, J. David Haynes et al. · Antimicrobial Agents and Chemotherapy · 1979 · 2.5K citations · Full text

, , +17

Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

David A. Fidock, Takashi Nomura, Angela K. Talley et al. · Molecular Cell · 2000 · 1.5K citations · Full text

, , +12

A Molecular Marker for Chloroquine-Resistant Falciparum Malaria

Abdoulaye Djimdé, O K Doumbo, Joseph F. Cortese et al. · New England Journal of Medicine · 2001 · 1K citations · Full text

, , +17

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

Michael B. Reed, Kevin J. Saliba, Sonia R. Caruana et al. · Nature · 2000 · 858 citations

, , +13