Concepedia

Diastereoselective Synthesis of Glycosyl-β-hydroxy-α-amino Esters

M. El Hadrami, Jean‐Pierre Lavergne, Ph. Viallefont, A. Chiaroni, C. Riche, A. Hasnaoui

Synthetic Communications · 1993 · 20 citations · 30 references

DOI

Concepts

Abstract

Abstract We report here the first synthesis of glycosyl-β-hydroxy-α-amino esters by the aldol condensation of a glycine enolate on the aldehyde function of a ribose (1a) or a galactose (1b).

References

30

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A mild and efficient route to Schiff base derivatives of amino acids

Martin O’Donnell, Robin Polt · The Journal of Organic Chemistry · 1982 · 345 citations

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Asymmetric glycine enolate aldol reactions: synthesis of cyclosporin's unusual amino acid, MeBmt

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Monocyclic β-lactam antibiotics produced by bacteria

R. B. Sykes, C. M. CIMARUSTI, D P Bonner et al. · Nature · 1981 · 300 citations

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Hydroxamate approach to the synthesis of .beta.-lactam antibiotics

Marvin J. Miller · Accounts of Chemical Research · 1986 · 215 citations

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