PubMed · 2007 · 147 citations · 16 references
NursingMaternal HealthPediatricsInfant HealthNeonatal HealthSubstance Use DisordersCare Of Premature InfantsInfant CareNeonatal Drug TherapyNeonatal NursingNeonatal SafetyNewborn CareFacility-based Newborn CareHospital Discharge AssessmentHospital Discharge PathwaysMaternal Substance UseNeonatal Abstinence SyndromeNeonatal Withdrawal SyndromeStandard Of Care ComparatorsSubstance-affected Infant Care
OBJECTIVE: To evaluate the effect of rooming-in (rather than standard nursery care) on the incidence and severity of neonatal abstinence syndrome among opioid-exposed newborns and on the proportion of mothers who retain custody of their babies at hospital discharge. DESIGN: Retrospective cohort study. SETTING: Lower mainland in southwestern British Columbia. PARTICIPANTS: We selected 32 women in the city of Vancouver known to have used heroin or methadone during pregnancy between October 2001 and December 2002. Comparison groups were a historical cohort of 38 women in Vancouver and a concurrent cohort of 36 women cared for in a neighbouring community hospital. MAIN OUTCOME MEASURES: Need for treatment with morphine, number of days of treatment with morphine, and whether babies were discharged in the custody of their mothers. RESULTS: Rooming-in was associated with a significant decrease in need for treatment of neonatal abstinence syndrome compared with the historical cohort (adjusted relative risk [RR] 0.40, 95% confidence interval [CI] 0.20 to 0.78) and the concurrent cohort (adjusted RR 0.39, 95% CI 0.20 to 0.75). Rooming-in was also associated with shorter newborn length of stay in hospital compared with both comparison groups. Newborns who roomed in at BC Women's Hospital were significantly more likely to be discharged in the custody of their mothers than babies in the historical cohort (RR 2.23, 95% CI 1.43 to 3.98) or the concurrent cohort (RR 1.52, 95% CI 1.15 to 2.53) were. CONCLUSION: Rooming-in might ease opioid-exposed newborns' transition to extrauterine life and promote more effective mothering.
16
Practical Statistics for Medical Research.
Sophie Walter, Daniel Altman · Biometrics · 1992 · 11.7K citations
Jessica M. Sontrop, Stephanie N. Dixon, Amit X. Garg et al. · American Journal of Nephrology · 2013 · 5.9K citations · Full text
Neonatal abstinence syndrome: assessment and management.
Finnegan Lp, Jr Jf Connaughton, RE Kron et al. · PubMed · 1975 · 668 citations
Medicine, Pediatrics, Pharmacology +17