Concepedia

Glucosamine hydrochloride functionalized tetraphenylethylene: A novel fluorescent probe for alkaline phosphatase based on the aggregation-induced emission

Qi Chen, Ning Bian, Chun Cao, Xilong Qiu, Ai‐Di Qi, Bao‐Hang Han

Chemical Communications · 2010 · 159 citations · 28 references

DOI

Concepts

Abstract

Grafting of glucosamine hydrochloride moieties to tetraphenylethylene (TPE) motif furnished a novel cationic water-soluble tetraphenylethylene derivative (GH-TPE). With aggregation-induced emission properties, GH-TPE was used for fluorometric detection to alkaline phosphatase through enzyme-triggered de-aggregation of the ensemble of GH-TPE and substrate.

References

28

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Hartmuth C. Kolb, M. G. Finn, K. Barry Sharpless · Angewandte Chemie International Edition · 2001 · 9.3K citations · Full text

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