Receptors for advanced glycation end-products (AGE)--expression by endothelial cells in non-diabetic uraemic patients

Abstract

Normal endothelial cells do not constitually express RAGE antigen; in contrast it is expressed by arterial and capillary endothelial cells of uraemic patients. The observation is of note in view of the putative role of AGE of causing atherosclerotic and non-atherosclerotic vascular lesions.