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Methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples of infertile couples correlates with recurrent spontaneous abortion

John Charles Rotondo, Sm Bosi, Erica Bazzan, Maura Di Domenico, Monica De Mattei, Rita Selvatici, Alfredo Patella, Roberto Marci, Mauro Tognon, Fernanda Martini

Human Reproduction · 2012 · 71 citations · 20 references

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Abstract

Our institution has received an FAR research grant from the University of Ferrara, Ferrara, Italy. No competing interests declared.

References

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Utility of the sperm chromatin structure assay as a diagnostic and prognostic tool in the human fertility clinic

D.P. Evenson · Human Reproduction · 1999 · 1.1K citations · Full text

Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition

Zhuo Chen · Human Molecular Genetics · 2001 · 611 citations

Widespread Epigenetic Abnormalities Suggest a Broad DNA Methylation Erasure Defect in Abnormal Human Sperm

Sahar Houshdaran, Victoria K. Cortessis, Kimberly D. Siegmund et al. · PLoS ONE · 2007 · 278 citations · Full text

SV40 early region and large T antigen in human brain tumors, peripheral blood cells, and sperm fluids from healthy individuals.

Fernanda Martini, Laura Iaccheri, L Lazzarin et al. · PubMed · 1996 · 206 citations

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Differential expression of imprinted genes in normal and IUGR human placentas

Andreas I. Diplas, Luca Lambertini, Men‐Jean Lee et al. · Epigenetics · 2009 · 181 citations · Full text

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