Concepedia

CYP1A-Mediated Metabolism of the Janus Kinase-3 Inhibitor 4-(4′-Hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: Structural Basis for Inactivation by Regioselective O-Demethylation

Fatih M. Uckun, Jason C. Thoen, Hao Chen, E. Sudbeck, Chen Mao, Ravi Malaviya, Xingping Liu, Chun‐Lin Chen

Drug Metabolism and Disposition · 2002 · 11 citations · 29 references

DOI

Concepts

References

29

SADABS, Program for Empirical Absorption Correction of Area Detector Data

George M. Sheldrick · Medical Entomology and Zoology · 1996 · 3.6K citations

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Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

Thomas Kronbach, Daniel Mathys, Makoto Umeno et al. · Molecular Pharmacology · 1989 · 535 citations

, , +15

LUDI: rule-based automatic design of new substituents for enzyme inhibitor leads

Hans-Joachim B�hm · Journal of Computer-Aided Molecular Design · 1992 · 459 citations

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Active anaphylaxis in IgE-deficient mice

Hans C. Oettgen, Thomas R. Martin, Anthony Wynshaw‐Boris et al. · Nature · 1994 · 426 citations

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Crystal structure and refinement of cytochrome P450terp at 2·3 Å resolution

Charles A. Hasemann, Kirubhagaran Ravichandran, Julian A. Peterson et al. · Journal of Molecular Biology · 1994 · 394 citations

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