Biomarkers in Medicine · 2015 · 77 citations · 23 references
MedicineCardiologyHematologyClinical CardiologyClinical EpidemiologyDiabetologyCardiac BiomarkersCardiac Risk AssessmentCardiovascular DiseaseIschemic Heart DiseasePlatelet FunctionPlatelet PhysiologyCardiac Outcome AssessmentCardiovascular BiomarkersIn-hospital MortalityLate MortalityMyocardial Infarction Risk StratificationPlatelet-to-lymphocyte RatioReceiver Operating Characteristic AnalysisRisk Factor Evaluation
AIM: Platelet-to-lymphocyte ratio (PLR) has emerged as a strong marker of worse outcomes. We determined the association between PLR and clinical outcomes in patients with diabetes mellitus and ST-elevation myocardial infarction. METHODS: Five hundred and twenty three patients were enrolled. Low PLR (group 1, n = 349) was defined as ≤ 124 and high PLR (group 2, n = 174) as >124. RESULTS: In-hospital and 1-year mortality was higher in group 2. Receiver operating characteristic analysis revealed moderate diagnostic value in predicting in-hospital (PLR cut-off >155) and long-term (PLR cut-off >146) death. PLR remained an independent risk factor of early and late mortality. CONCLUSION: PLR proved to have good prognostic value for in-hospital and late mortality. PLR cut-off value for predicting in-hospital mortality was higher to that predicting late mortality. PLR remained an independent risk factor early and late mortality.
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L Rydén, Eberhard Standl, M. Bartnik et al. · European Heart Journal · 2006 · 1.7K citations · Full text
Medicine, Cardiology, Endocrinology +17
Guidelines for Percutaneous Coronary Interventions
Sigmund Silber, Per Albertsson, Francisco Fernández‐Avilés et al. · European Heart Journal · 2005 · 1.6K citations · Full text