Artificial Bacterial Flagella for Remote‐Controlled Targeted Single‐Cell Drug Delivery

Rami Mhanna, Famin Qiu, Li Zhang, Yun Ding, Kaori Sugihara, Marcy Zenobi‐Wong, Bradley J. Nelson

Small · 2014 · 207 citations · 38 references

Concepts

Abstract

An approach for batch preparation of liposome-functionalized microdevices is demonstrated for remotely controlled single-cell drug delivery. The liposome functionalized artificial bacterial flagella exhibit corkscrew swimming in 3D with micrometer positioning precision by applying an external rotating magnetic field. The devices are also capable of delivering water-soluble drugs to single cells in vitro.

References

38