Concepedia

Publication | Open Access

CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

DOIFull Paper Access

83

Citations

19

References

2015

Year

A Wilhelm, Victoria Aldridge, Debashis Haldar, Amy J. Naylor, Chris J. Weston, Ditte L. Hedegaard, Abhilok Garg, Janine Fear, Gary Reynolds, Adam P. Croft,
Gut

Abstract

Our data show that deletion of CD248 reduces susceptibility to liver fibrosis via an effect on PDGF signalling, making it an attractive clinical target for the treatment of liver injury.

References

YearCitations

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