Poultry Science · 1980 · 39 citations · 12 references
AgriculturePoultry SciencePoultry HealthPoultry MedicinePoultry NutritionBacterial Diseases Of PoultryBroiler Growth PerformanceBroiler NutritionPoultry BacteriologyPoultry Disease PreventionPoultry Infectious DiseasesAnimal Weight GainAntimicrobial Use In PoultryBroiler Coccidiosis ControlControl Of Bacterial DiseasesDose Response EffectsFeed Consumption RateMain Effects
Salinomycin (Coxistac) was tested for efficacy in broilers reared in floor pens at 60 and 80 ppm fed continuously from 1 to 56 days of age. One trial was conducted. Comparisons were made with unmedicated, infected and medicated, noninfected treatments (controls) in addition to infected treatments given either monensin at 100 ppm or halofuginone at 3 ppm continuously (days 1 to 56) in the feed. Coccidia exposure was obtained by infection via the feed. Salinomycin was highly efficacious at 60 ppm based upon improved performance, lesion score, hematocrit, and serum optical density compared with the unmedicated, infected group. Statistical analysis of main effects on weight gain, feed conversion ratio, hematocrit value, and serum optical density showed no significant differences between salinomycin, monensin, or halofuginone. The weight gain of birds given salinomycin at 80 ppm was depressed significantly (P less than .01) at 56 days as a result of decreased feed consumption.
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Multiple Range and Multiple F Tests
David B. Duncan · Biometrics · 1955 · 23.2K citations
The structure of salinomycin, a new member of the polyether antibiotics
Haruyasu Kinashi, NOBORU OTAKE, Hiroshi Yonehara et al. · Tetrahedron Letters · 1973 · 130 citations
Anticoccidial Activity of Salinomycin in Battery Raised Broiler Chickens
Harry D. Danforth, M. D. Ruff, W. Malcolm Reid et al. · Poultry Science · 1977 · 65 citations · Full text