NON-SURGICAL CONTRACEPTION IN FEMALE DOGS AND CATS

Abstract

Gonadectomy is the most commonly used method for permanent contra- ception in small animals. The irreversibility of the method is however a main drawback for its use in valuable breeding animals. Moreover, several negative side effects can be observed after surgical castration. Therefore several non-surgical methods were developed. This paper describes the current non-surgical methods of contraception used in female dogs and cats. They include hormonal procedures, such as application of progestins, androgens and GnRH analogues in order to prevent the ovarian cycle. Another method is the use of 4-vinylcyclohexene diepoxide, an industrial chemical destroying primordial and primary ovarian follicles. Further prospective possibilities consist in immunocontraception and in the elaboration of a safe and effective vaccine with reversible effect. Finally the use of several abortive drugs, such as aglepristone, PGF2 and dopamine agonists are presented.