APOE and Alzheimer disease: a major gene with semi-dominant inheritance

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

Ann M. Saunders, Warren J. Strittmatter, D. E. Schmechel et al. · Neurology · 1993 · 3.8K citations · Full text

Life Sciences, Genetics, Neurology +17

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Denise Harold, Richard Abraham, Paul Hollingworth et al. · Nature Genetics · 2009 · 3.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

Jean‐Charles Lambert, Simon Heath, Gaël Even et al. · Nature Genetics · 2009 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +12

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

Lindsay A. Farrer · JAMA · 1997 · 1.9K citations

Medicine, Genetics, Neurology +17

Genetic associations with human longevity at the APOE and ACE loci

François Schächter, Laurence Faure-Delanef, Frédérique Guénot et al. · Nature Genetics · 1994 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +14