Bioinformatics · 2009 · 94 citations · 6 references
Life SciencesBioinformaticsBiostatisticsComputational BiologyGene ExpressionGenomicsGene Co-expression AnalysisGene Coexpression NetworksCoexpression Network AnalysisGene Co-expression Network AnalysisGene Expression Network AnalysisGene Network AnalysisInformation Theory In BiologyNetwork-based Association AnalysisPartial Correlation NetworksWeighted Networks
SUMMARY: We make the PCIT algorithm, used for detecting meaningful gene-gene associations in co-expression networks, available as an R package. Automatic detection of a suitable parallel environment is used such that scripts are portable between parallel and non-parallel environments with no modification of the script. AVAILABILITY AND IMPLEMENTATION: Source code and binaries freely available (under GPL-3) for download via CRAN at http://cran.r-project.org/package=PCIT, implemented in R and supported on Linux and MS Windows.
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Reverse engineering of regulatory networks in human B cells
Katia Basso, Adam A. Margolin, Gustavo Stolovitzky et al. · Nature Genetics · 2005 · 1.4K citations