Concepedia

Fibrate and Statin Synergistically Increase the Transcriptional Activities of PPARα/RXRα and Decrease the Transactivation of NFκB

Ikuo Inoue, Fumiaki Itoh, Shigemi Aoyagi, Shigeki Tazawa, Hiroshi Kusama, Masuo Akahane, Toshiyuki Mastunaga, Kenji Hayashi, Takuya Awata, Tugikazu Komoda,

Biochemical and Biophysical Research Communications · 2002 · 114 citations · 18 references

DOI

Concepts

References

18

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

Isabelle Issemann, Stephen Green · Nature · 1990 · 3.5K citations

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mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

Peter Tontonoz, E Hu, Reed A. Graves et al. · Genes & Development · 1994 · 2.2K citations · Full text

, , +17

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Hitoshi Shimano, Jay D. Horton, Iichiro Shimomura et al. · Journal of Clinical Investigation · 1997 · 834 citations · Full text

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Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Hitoshi Shimano, Jay D. Horton, Robert E. Hammer et al. · Journal of Clinical Investigation · 1996 · 818 citations · Full text

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Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

Jay D. Horton, Iichiro Shimomura, Matthew Brown et al. · Journal of Clinical Investigation · 1998 · 707 citations · Full text

, , +17