Concepedia

Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro

Hanna Ksiȩżak-Reding, Han Kyoung Pyo, Boris Feinstein, Giulio Maria Pasinetti

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2003 · 130 citations · 39 references

DOI

Concepts

References

39

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al. · Cell · 1995 · 2K citations · Full text

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Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

Teresa Gómez‐Isla, Richard Hollister, Howard West et al. · Annals of Neurology · 1997 · 1.5K citations

, , +12

Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

Vuk Stambolic, Laurent Ruel, James R. Woodgett · Current Biology · 1996 · 1.3K citations · Full text

, , +10

Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms

Michel Goedert, Maria Grazia Spillantini, Nigel J. Cairns et al. · Neuron · 1992 · 1.1K citations

, , +16

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Kathrin Gottlob, Nathan Majewski, Scott Kennedy et al. · Genes & Development · 2001 · 948 citations · Full text

, , +17