Clinical and Vaccine Immunology · 2007 · 23 citations · 22 references
Life SciencesGeneticsImmunologyImmunizationImmunogeneticsVaccine ImmunologyImmune Response To VaccinationInnate Immune Gene PolymorphismsInnate Immune ReceptorsPattern Recognition ReceptorsToll-like ReceptorsVaccinationImmune Response Gene Polymorphism AnalysisSingle-nucleotide PolymorphismsTag Single Nucleotide PolymorphismsToll-like Receptor 4 GeneticsToll-like Receptor Gene PolymorphismsToll-like Receptor HaplotypesToll-like Receptor SignalingWhole-cell Vaccines
We examined the association between haplotype tagging single-nucleotide polymorphisms in TLR4 and the pertussis toxin-specific immunoglobulin G response after whole-cell pertussis (wP) vaccination in 515 1-year-old children from the KOALA study. A lower titer was associated with the minor allele of rs2770150, supporting a role for Toll-like receptor 4 in the antibody response to wP vaccination.
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Haploview: analysis and visualization of LD and haplotype maps
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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene
Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations
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Life Sciences, Genetics, Immunology +10
Doreen M. Agnese, Jacqueline E. Calvano, Sae J. Hahm et al. · The Journal of Infectious Diseases · 2002 · 569 citations · Full text